PhD Position on Biophysical Origins of RNA Toxicity in Huntington’s Disease

PhD Position on Biophysical Origins of RNA Toxicity in Huntington’s Disease Utrecht University via AcademicTransfer Biological sciences » BiologyMedical sciences » MedicineNeurosciences » NeurobiologyPhysics » Biophysics In Huntington’s Disease (HD), expansion of CAG repeats in the huntingtin (HTT) gene leads to a toxic gain-of-function that ultimately results in fatal neurodegeneration. HD research has long focused on the toxic effects of the HTT-encoded polyglutamine protein that aggregates in neurons. However...